Week 10’s early games on Sunday feature standout matchups between playoff-contending teams with winning records.
The 5-4 New Orleans Saints head to Minnesota, with the Vikings seeking a fifth consecutive win under the unexpected leadership of Joshua Dobbs.
The San Francisco 49ers visit the Jacksonville Jaguars, hoping to snap a three-game skid and mark the anticipated debut of newly-traded edge rusher Chase Young.
Finally, an intense AFC North encounter pits the Baltimore Ravens, led by an in-form Lamar Jackson, against the Cleveland Browns with both teams boasting elite defences allowing only 13.8 and 17.4 points per game, respectively.
Read on for our NFL Week 10 preview along with our NFL best bets based on the latest NFL odds.
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NFL Week 10 Schedule
Thursday
Carolina Panthers vs Chicago Bears
Sunday
Indianapolis Colts vs New England Patriots
San Francisco 49ers vs Jacksonville Jaguars
Houston Texans vs Cincinnati Bengals
Cleveland Browns vs Baltimore Ravens
New Orleans Saints vs Minnesota Vikings
Tennessee Titans vs Tampa Bay Buccaneers
Green Bay Packers vs Pittsburgh Steelers
Detroit Lions vs Los Angeles Chargers
Atlanta Falcons vs Arizona Cardinals
New York Giants vs Dallas Cowboys
Washington Commanders vs Seattle Seahawks
New York Jets vs Las Vegas Raiders
Monday
Denver Broncos vs Buffalo Bills
San Francisco 49ers vs. Jacksonville Jaguars
After a strong start with five straight victories, the San Francisco 49ers have hit a rough patch, dropping three games in a row.
They aim to get back to winning ways against the 6-2 Jacksonville Jaguars, who have found their rhythm after an initial setback, currently riding a five-game win streak with an impressive 11-point average victory margin, signalling their rise in the AFC.
Travis Etienne Jr. has been instrumental in Jacksonville’s success, scoring seven touchdowns in four games and will likely be key once again in Week 10.
The Jaguars, aiming for the AFC’s top positions and a playoff bye, will likely lean on Etienne’s dynamic play against the 49ers.
Surprisingly, the Jaguars are considered three-point underdogs at home, despite their form and a five-game streak of covering the spread.
They face a 49ers team that’s struggling offensively on the road, which could spell another win for Jacksonville as they look to extend their successful run.
Picks: Jaguars +3 @ 1.93
New Orleans Saints vs Minnesota Vikings
The New Orleans Saints have surged into NFC South leadership thanks to consecutive victories, a stunning turnaround in a division where last year’s top team secured only 8 wins.
Scoring an average of 21.7 points and conceding 19 per game, the Saints boast the 8th ranked defence in the NFL.
Derek Carr’s performance has flown under the radar this season, amassing 2,121 passing yards and 10 touchdowns.
Taysom Hill has also contributed significantly with a touchdown in the air, three on the ground, and one receiving while Alvin Kamara remains a formidable dual-threat with 346 rushing yards and 272 receiving yards.
As they embark on successive road games, the Saints encounter a 5-4 Vikings squad with a surprisingly weak 1-3 home record.
While the Vikings orchestrated a recovery against the Falcons, they now face a Saints team that, despite not having beaten a currently winning team, holds a solid 3-2 record on the road.
The Vikings won 28-25 last season but expect the Saints return the favour as they aim to solidify their playoff prospects.
Pick: Saints -2.5 @ 1.88
Baltimore Ravens vs Cleveland Browns
In Week 9, the Baltimore Ravens delivered a masterclass performance, dismantling the Seahawks with a resounding 37-3 victory.
What stood out was their ability to dominate without relying on Lamar Jackson’s arm for touchdowns. Instead, the Ravens showcased their ground prowess, charging into the end zone three times with their rushing attack.
With the game comfortably in hand, backup Tyler Huntley stepped in and connected with Odell Beckham Jr. for a score.
Incorporating OBJ into an offense already boasting talents like Zay Flowers and Mark Andrews could seriously bolster their campaign, propelling Baltimore into discussions as a top contender in the AFC.
Looking ahead to Week 10, the Ravens face a Browns team coming off a commanding win. However, Cleveland’s triumph came against a compromised Cardinals squad, who had just parted ways with Josh Dobbs.
When the Browns meet the Ravens, they’re likely to encounter a far sterner test. Baltimore, riding high on confidence and strategic execution, seems poised to deliver a stark wake-up call to Cleveland in the upcoming encounter.
Pick: Ravens -4.5 @1.72
NFL Week 10 Picks & NFL Best Bets
Jacksonville Jaguars +3 @ 1.93 vs San Francisco 49ers
New Orleans Saints -2.5 @ 1.88 vs Minnesota Vikings
Baltimore Ravens -4.5 @1.72 vs Cleveland Browns
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