Arsenal are looking to go one better in the Champions League after falling at the final hurdle in 2025-26.
The Gunners lost on penalties to Paris Saint-Germain in last season’s final, though their Premier League title win softened the blow somewhat.
However, Mikel Arteta will now be more desperate than ever to add Europe’s biggest footballing prize to his managerial CV, but a trip to Napoli on Matchday 1 of the League Phase is far from the easiest of starts!
Below is our full sports betting preview for Wednesday’s intriguing clash in Naples, complete with tips and the latest Champions League odds on NetBet Sport.
And if you are looking to place a Champions League combo bet this week, remember that our Acca Boost feature can increase your potential winnings by up to 50%!
Where can I watch Napoli vs Arsenal in the UK?
Napoli vs Arsenal will be broadcast live on TNT Sports 2, with kick-off scheduled for 8pm UK time.
Napoli vs Arsenal Preview
Recent results
Arsenal made it three wins from three in the Premier League last Sunday courtesy of a 2-1 victory over London rivals Chelsea. Kai Havertz and Martin Odegaard grabbed the goals to seal three more points for the Premier League champions, with the Gunners also claiming a vital 1-0 win at Aston Villa last Monday.
After a 2-0 triumph at Genoa on the opening weekend of the Serie A season, Napoli suffered back-to-back losses vs FC Como (1-2) and Inter Milan (3-2). Max Allegri’s side took a 2-0 lead in the latter fixture, only for the Italian champions to romp to a comeback victory in the second half at San Siro.
Head-to-head record
These two sides last met in the Champions League way back in 2013. Arsenal won 2-0 at home in the group stage, but also suffered a 2-0 defeat in Naples.
The teams did collide more recently in the Europa League, a knockout tie which saw the Gunners win 3-0 on aggregate after backing up a 2-0 victory at the Emirates with a 1-0 away success.
Team news
Scott McTominay is set to miss around a month for Napoli as the midfielder undergoes a minor heart operation. Central defenders Alessandro Buongiorno and Luca Marianucci are also ruled out for the hosts. Kevin De Bruyne – a tormentor of Arsenal in the past – is yet to start a game this season, but could be brought in here given his record against the Gunners (eight goals and five assists in 22 previous appearances!).
William Saliba remains a long-term absentee for Arsenal, while Jurrien Timber and Cristhian Mosquera are also unlikely to feature here. Declan Rice and Bruno Guimaraes have been managing knocks of late, so do not be surprised if Arteta enforces some kind of midfield rotation in Naples.
Napoli vs Arsenal Odds
*All odds are subject to change
Arsenal arrive in Italy as favourites to claim the victory, priced as low as 1.72. A win for Napoli is at odds 4.60, while the draw here is 3.53.
Napoli vs Arsenal Betting Tips
Total goals – Over 2.5 @ 1.85
While Arsenal are famed for their defensive prowess, goals have still been a common theme in their matches this season. Over 2.5 were scored in three out of four games, while the selection also landed in Napoli’s previous two Serie A fixtures.
Both teams to score – Yes @ 1.78
Morgan Rogers’ strike at the Emirates last Sunday was the first goal conceded by Arsenal in 2026-27. And with injuries (Saliba, Timber and Mosquera) at the back piling up a tad, clean sheets may not be as easy to come by in the coming weeks. Furthermore, Napoli possess some potent attackers, including two-goal Rasmus Hojlund – and the Neapolitans scored at least once in 12 of the last 13 games hosted at the Diego Armando Maradona Stadium.
Anytime goalscorer – Kai Havertz @ 2.70
After striking three times in four matches for Germany at World Cup 2026, Havertz is back delivering in an Arsenal jersey. The striker has three goals in four appearances this season, including the crucial equaliser vs Chelsea last Sunday. Against a wounded Napoli back-line, Havertz can land another decisive blow in a big game.
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