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NFL Week 16: Preview, Predictions, Picks & NFL Best Bets

NFL Week 16 Preview

With the holiday season in full swing, the NFL schedule is full to bursting point featuring games on Thursday, Saturday, Sunday, and Monday for the second consecutive week.

As we enter the crucial final stretch, the stakes for each game are getting bigger, particularly for those teams still vying for a playoff spot.

The highlight of the Week 16 slate is the Sunday afternoon clash between the Cowboys and Dolphins.

Additionally, there are numerous pivotal matchups on the schedule, featuring teams teetering on the edge of postseason qualification.

This makes for an exciting and decisive week in the NFL, so here are our NFL Week 16 picks and best bets based on the latest NFL odds.

You can take your sports betting experience up a notch with BetPlus, offering enhanced odds on 1×2 odds on the biggest events.

NFL Week 16 Schedule

Thursday

New Orleans Saints at Los Angeles Rams

Saturday

Cincinnati Bengals at Pittsburgh Steelers

Buffalo Bills at Los Angeles Chargers

Sunday

Cleveland Browns at Houston Texans

Detroit Lions at Minnesota Vikings

Seattle Seahawks at Tennessee Titans

Indianapolis Colts at Atlanta Falcons

Green Bay Packers at Carolina Panthers

Washington Commanders at New York Jets

Jacksonville Jaguars at Tampa Bay Buccaneers

Arizona Cardinals at Chicago Bears

Dallas Cowboys at Miami Dolphins

New England Patriots at Denver Broncos

Monday

Las Vegas Raiders at Kansas City Chiefs

New York Giants at Philadelphia Eagles

Baltimore Ravens at San Francisco 49ers

Miami Dolphins vs. Dallas Cowboys

The Miami Dolphins didn’t miss a beat without Tyreek Hill, dominating the New York Jets in a 30-0 victory in Week 15, controlling the game from start to finish.

Despite a hiccup in Week 14 where they lost a double-digit lead, the Dolphins have successfully covered the spread in three of their last four games.

Although Miami hasn’t faced another top-tier team since their encounter with the Kansas City Chiefs in Week 9, choosing Dallas isn’t a sure bet.

The Cowboys have shown a stark contrast in their performance at home versus on the road in 2023. They boast a perfect 7-0 record with an impressive +171-point differential at AT&T Stadium, but their record dips to 3-4 with a -4 differential in away games.

There’s potential for a high-scoring affair with two strong offenses that often exceed the game totals, but the Cowboys’ road struggles this season are a concern and with the expected return of Hill, the Dolphins are well-positioned to cover the modest spread.

Pick: Dolphins -2.5 @ 1.83

Denver Broncos vs. New England Patriots

In their last game, Denver experienced a challenging start, with the first quarter ending scoreless.

However, they quickly lost ground as the Detroit Lions scored touchdowns on five successive drives, putting Denver in a daunting 35-10 deficit early in the fourth quarter.

Despite this setback, Denver has maintained a strong home record, winning their last four games at the Mile High Stadium, following a streak of three consecutive home losses.

This game presents an excellent opportunity for Denver’s defence to regain its form. In six of their last eight games, they have held opponents to under 20 points, including in all four recent home games.

Facing a New England offense led by Bailey Zappe, especially in Denver’s high-altitude environment, the Broncos’ defence is well-positioned for a strong performance as they aim to continue their winning streak.

Pick: Broncos -6.5 @ 1.94

Houston Texans vs. Cleveland Browns

Last weekend, the Houston Texans staged an impressive comeback, overcoming a 13-3 halftime gap to clinch a 19-16 overtime victory against the Tennessee Titans, with backup quarterback Case Keenum leading the charge.

This week the team’s prospects are further bolstered with the return of second overall draft pick, quarterback C.J. Stroud, and wide receiver Nico Collins.

This comeback sets the stage for a high-scoring game, where an ‘over’ seems likely.

Stroud’s impact has been significant, with the team scoring 20 or more points in all seven of their home games this season.

In three of these games, they have exceeded the over, indicating a trend that might continue in this upcoming matchup.

Pick: Over 42.5 Points @ 1.88

NFL Week 16 Picks & NFL Best Bets

Dolphins -2.5 @ 1.83 vs Cowboys

Broncos -6.5 @ 1.94 vs Patriots

Texans vs. Browns: Over 42.5 Points @ 1.88

*Odds subject to change.

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