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NFL Week 12: Preview, Predictions, Picks & NFL Best Bets

NFL Week 12 Picks

NFL Week 11 was packed with excitement and drama with the Giants defeating the Commanders and comeback victories such as the Rams’ 10-point rally against the Seahawks.

But now our attention shifts to Week 12, highlighted by a Thanksgiving triple-header and a Black Friday game.

A full slate of 16 matchups awaits us in Week 12 with three games on Thanksgiving kicking things off not to mention plenty of intriguing action on Friday, Sunday and Monday.

Read on for our NFL Week 12 preview along with our NFL best bets based on the latest NFL odds.

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NFL Week 12 Schedule

Thursday

Green Bay Packers vs Detroit Lions

Washington Commanders vs Dallas Cowboys

San Francisco 49ers vs Seattle Seahawks

Friday

Miami Dolphins vs New York Jets

Sunday

New Orleans Saints vs Atlanta Falcons

Pittsburgh Steelers vs Cincinnati Bengals

Jacksonville Jaguars vs Houston Texans

Tampa Bay Buccaneers vs Indianapolis Colts

New England Patriots vs Tennessee Titans

LA Rams vs Arizona Cardinals

Cleveland Browns vs Denver Broncos

Kansas City Chiefs vs Las Vegas Raiders

Buffalo Bills vs Philadelphia Eagles

Baltimore Ravens vs LA Chargers

Monday

Chicago Bears vs Minnesota Vikings

Pittsburgh Steelers vs. Cincinnati Bengals

The Steelers, with Kenny Pickett as their quarterback, arguably have a more stable offensive advantage than the Bengals, who are now without Joe Burrow.

Despite this advantage, Pittsburgh struggled in their recent game against a Browns team missing Deshaun Watson.

However, the upcoming matchup offers an opportunity for the Steelers to improve their running game and exploit the injuries plaguing their rivals.

Cincinnati is facing a significant shift in Week 12, entering a phase without their star quarterback Joe Burrow, who sustained a season-ending wrist injury.

Pittsburgh’s road performance this season stands at 2-2 ATS, including a failure to cover in their only game as a road favourite.

With the Steelers’ games trending towards low scores, indicated by an 8-2 record for the Under, and the Bengals fielding an untested quarterback in Jake Browning, this game is likely to be another low-scoring affair with Pittsburgh coming out on top.

Pick: Steelers -1 @ 1.91

New York Giants vs. New England Patriots

For bettors eyeing high-scoring games, the Week 12 Patriots vs. Giants clash, with the lowest total on the board at 33.5, might not be the top choice.

While both teams are not known for explosive offenses, the Giants did turn heads with a 31-point victory against the Commanders, where Tommy DeVito scored three touchdowns.

Despite this, the Patriots, coming off a bye week, are still the 3.5-point favourites on the road.

New England’s track record on the road shows a 1-3 ATS, contrasting with the Giants’ 1-2-1 ATS at home, indicating a potentially close contest.

This matchup presents an intriguing scenario for bettors, with defensive prowess likely taking centre stage and making the Under the most appealing wager.

Pick: Under 33.5 Points @ 1.94

Cleveland Browns vs. Denver Broncos

In the AFC, both the Browns and the Broncos are in fine form, actively contending for a playoff spot.

The Browns, now at 7-3, secured their position as a wild card team with a recent victory over the Steelers, overcoming the loss of Deshaun Watson for the season.

The Broncos, on a four-game winning streak, have reached an even .500 for the year. In this Week 12 matchup, Denver is slightly favoured by 1.5 points, but their home betting record is less convincing.

Under Sean Payton, they are 2-4 ATS at home, including a recent miss against Minnesota in Week 11.

The Browns haven’t been particularly dominant on the road, standing at 1-2-1 ATS away from Cleveland Browns Stadium.

With a low over/under at 36.5, this game is shaping up to be a tight contest, suggesting a tight battle where defensive play could be the deciding factor with Denver just sneaking it.

Pick: Denver Broncos -2.5 @

NFL Week 12 Picks & NFL Best Bets

Pittsburgh Steelers -1 @ 1.91 vs Cincinnati Bengals

New York Giants vs New England Patriots: Under 33.5 Points @ 1.94

Denver Broncos -2.5 @ 1.91 vs Cleveland Browns

*Odds subject to change.

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